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Actinomycin D 现货促销，7折优惠！
629 人阅读发布时间：2013-05-28 13:56
产品名称：Actinomycin D
化学名：1-oxo-2,1-ethanediyl)-1,2-pyrrolidinediylcarbonyl(methylimino)(1-oxo-2,1-ethan
CAS No：50-76-0
分子式：C62H86N12O16
分子量：1255.44
纯度：≥98%
溶解度：Soluble in DMSO (>20 mg/ml), 100% ethanol (1 mg/ml)
保存：-20° C
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货号：abs810015
规格：大包装询价
货号 产品名称 规格
abs810015a Actinomycin D 5mg
abs810015b Actinomycin D 10mg
abs810015c Actinomycin D 25mg
abs810015d Actinomycin D 50mg
abs810015e Actinomycin D 100mg
库存：现货
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生物活性：
Actinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA.
The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram
negative bacteria. Actinomycin D can induce apoptosis in several cell lines such as lung and prostate
cancer lines, and human blood lymphocytes, among others. This compound is also an RNA polymerase
inhibitor. In studies it has been observed that Actinomycin D elevates p53 expression, leading to the
increase of PUMAα/β (the p53 upregulated modulator of apoptosis protein; PUMA), and can also induce
tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced caspase-dependent and
-independent apoptosis.