
产品名称:Brefeldin A
化学名:1,6,7,8,9,11aβ,12,13,14,14αa-Decahydro-1β, 13α- dihydroxy -6β-
methyl-4H-cyclopent(f)oxacyclotridecin-4-one
CAS No:20350-15-6
分子式:C16H24O4
分子量:280.36
纯度:98%
溶解度:Soluble to 50 mM in DMSO and to 10 mM in ethanol
保存: -20℃
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货号:abs810012
规格: 大包装询价
库存:现货
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生物活性:
Brefeldin A is a fungal metabolite (a macrocyclic lactone) which exhibits a wide range of antibiotic activity.
Brefeldin A (BFA) may be used to study cell processes which depend upon intracellular protein
transport.
Reversible inhibitor of protein translocation from the endoplasmic reticulum (ER) to the Golgi apparatus.
Blocks binding of ADP-ribosylation factor to the Golgi apparatus and inhibits GDP-GTP exchange. Can
be used to induce autophagy in mammalian cells.