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(19E/Z)-seco-[4-O-[2-Hydroxy(ethyl)-d4]] Rapamycin Sodium Salt
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Rapamycin 现货促销，7折优惠！
575 人阅读发布时间：2013-05-28 13:57
产品名称：Rapamycin
化学名：23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
CAS No：53123-88-9
分子式：C51H79NO13
分子量：914.17
纯度：＞ 99%
溶解度：Soluble to 20 mM in ethanol and to 50 mM in DMSO
保存： -20 ºC
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货号：abs810030
规格：大包装询价
货号 产品名称 规格
abs810030a Rapamycin 5mg
abs810030b Rapamycin 10mg
abs810030c Rapamycin 25mg
abs810030d Rapamycin 50mg
abs810030e Rapamycin 100mg
库存：现货
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生物活性：
Rapamycin is a macrocyclic triene antibiotic possessing potent immunosuppressant and anticancer activity.
It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR).
mTOR is a member of the phosphoinositide kinase-related kinase (PIKK) family that enhances cellular
proliferation via the phosphoinositol 3-kinase/Akt signaling pathway. Inhibition of this pathway by rapamycin
blocks downstream elements that result in cell cycle arrest in G1. The effectors of mTOR action include
4EBP1 and S6K1..