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SB202190,152121-30-7
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SB 202190 现货7折促销啦！
639 人阅读发布时间：2013-05-28 14:02
产品名称：SB 202190
化学名：4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol
CAS No：152121-30-7
分子式：C20H14N3OF
分子量：331.34
纯度：≥98%
溶解度：Soluble in DMSO, 30 mg/ml
保存：-20° C
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货号：abs810009
规格： 大包装询价
货号 产品名称 规格
abs810009a SB 202190 5mg
abs810009b SB 202190 10mg
abs810009c SB 202190 25mg
abs810009d SB 202190 50mg
abs810009e SB 202190 100mg
库存：现货
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生物活性：
SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway. The compound inhibits the isoforms p38α
and p38β. SB 202190 has displayed the ability to activate CPP32-like caspases and induce apoptosis.
Research demonstrates that when one residue of ERK2, a related p38 not inhibited by pyridinyl imidazoles,
is changed it allows SB 202190 to bind. Studies have revealed that SB 202190 can improve leukemia cell
growth by activating MEK/MAPK, as well as phosphorylate and activate MLK3.