
产品名称:17-AAG
化学名:17-Demethoxy-17-(2-propenylamino)geldanamycin
CAS No:75747-14-7
分子式:C31H43N3O8
分子量:585.7
纯度:98%
溶解度:Soluble in DMSO (10 mg/ml), in methanol (10 mg/ml) and in chloroform (10 mg/ml),
yielding a clear purple solution.
保存: -20℃
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货号:abs810017
规格: 大包装询价
货号 产品名称 规格
abs810017a 17-AAG 5mg
abs810017b 17-AAG 10mg
abs810017c 17-AAG 25mg
abs810017d 17-AAG 50mg
abs810017e 17-AAG 100mg
库存:现货
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生物活性:
17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer,
specific young patients with certain types of leukemia or solid tumors, especially kidney tumors.
It works by inhibiting Hsp90, which is expressed in those tumors.It belongs to the family of drugs called
antitumor antibiotics.
17-AAG is a potent Inhibitor of heat shock protein 90 (Hsp90) function. Hsp90 is a molecular chaperone
whose association is required for the stability and function of multiple mutated, chimeric, and
over-expressed signaling proteins that promote cancer cell growth and/or survival.