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(1R,2R,4S)-4-{(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-二羟基-19,30-二甲氧基-15,17,21,23,29,35-六甲基-2,3,10,14,20-五氧代-11,36-二氧杂-4-氮杂三环[30.3.1.0<sup>4,9</sup>,162635-03-2
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公司新闻/正文

17-AAG 现货7折促销啦,绝对最低价!

750 人阅读发布时间:2013-05-28 14:05

新闻图片1
产品名称:17-AAG
化学名:17-Demethoxy-17-(2-propenylamino)geldanamycin
CAS No:75747-14-7
分子式:C31H43N3O8
分子量:585.7
纯度:98%
溶解度:Soluble in DMSO (10 mg/ml), in methanol (10 mg/ml) and in chloroform (10 mg/ml), 
yielding a clear purple solution. 
保存: -20℃
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货号:abs810017
规格: 大包装询价
货号                产品名称     规格
abs810017a   17-AAG    5mg
abs810017b   17-AAG    10mg
abs810017c   17-AAG    25mg
abs810017d   17-AAG    50mg
abs810017e   17-AAG    100mg
库存:现货
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生物活性:
17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, 
specific young patients with certain types of leukemia or solid tumors, especially kidney tumors.
It works by inhibiting Hsp90, which is expressed in those tumors.It belongs to the family of drugs called 
antitumor antibiotics.
17-AAG is a potent Inhibitor of heat shock protein 90 (Hsp90) function. Hsp90 is a molecular chaperone 
whose association is required for the stability and function of multiple mutated, chimeric, and 
over-expressed signaling proteins that promote cancer cell growth and/or survival.

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