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JAK/STAT Inhibitor kit

￥6573

爱必信(上海)生物科技有限公司
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JAK/STAT、MAPK、PI3K/Akt、Wnt、G-Protein 等通路调节剂

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JAK/STAT、MAPK、PI3K/Akt、Wnt、G-Protein 等通路调节剂

1089 人阅读发布时间：2014-09-24 11:10

更新时间：2014/9/9 点击次数： 37


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Biochemical
quality
guarantee

High purity biochemicals
Abcam Biochemicals offers a range of the highest quality biochemical tools including agonists, antagonists, ion channel modulators, enzyme inhibitors and more.

Highest quality and purity
Our team has decades of synthetic chemistry experience - gained in diverse settings such as pharmaceutical labs, life science suppliers and academia. Our biochemicals are of very high purity, typically >98%. Chemical purity and quality are determined using a comprehensive range of techniques, including HPLC, chiral HPLC, NMR, microanalysis, optical rotation, TLC, and mass spectrometry. Details are provided on the Certificate of Authenticity that accompanies each product, and these are also available online.

Abcam Biochemicals are novel compounds and we have not tested their biological activity in house.

Please use the literature to identify how to use these products effectively. If you require further assistance please contact the scientific support team.

Cytokines, NF-κB & IκB

Cat No.	Compound	Description
ab120718	AMD3100 octahydrochloride	Highly selective CXCR4 antagonist
ab120862	Caffeic acid	Specific NF-κB inhibitor
ab120655	Celastrol from Celastrus scandens	Anti-inflammatory and anti-proliferative agent
ab120647	Honokiol	Anti-inflammatory and chemotherapeutic agent
ab120662	Luteolin	Antioxidant, anti-inflammatory, anti-cancer flavonoid
ab120725	Pentoxifylline	Phosphodiesterase inhibitor. Cytokine inhibitor
ab120746	Sodium salicylate	Cell permeable anti-inflammatory agent
ab120643	Tranilast	Anti-inflammatory agent
ab120720	Triptolide from Tripterygium wilfordii	Anti-inflammatory agent with multiple biological activities

G-Protein related

Cat No.	Compound	Description
ab120860	(+)-Abscisic acid	Phytohormone; produced by a variety of cells in humans and animals

Hedgehog signaling

Cat No.	Compound	Description
ab120392	Cyclopamine	Hh signaling inhibitor
ab120665	GANT58	Downstream Hh signaling inhibitor
ab120815	Jervine	Smoothened inhibitor
ab120819	JK 184	Potent Hedgehog signaling inhibitor

Inositol & cAMP signaling

Cat No.	Compound	Description
ab120493	Adenosine 3′,5′-cyclic monophosphate (cAMP)	Second messenger. PKA activator.
ab120124	2-APB	Ca²⁺ release modulator
ab120424	8-(4-Chlorophenylthio)adenosine 3’,5’-cyclic monophosphate (8-CPT-cAMP)	Cell permeable cAMP analogue, protein kinase modulator
ab120058	Forskolin	Adenylyl cyclase activator
ab120341	H89 dihydrochloride	Kinase inhibitor
ab120190	NKH 477 (Colforsin daropate)	Water-soluble analogue of forskolin (ab120058), an adenylyl cyclase activator
ab141115	scyllo-Inositol	Endogenous inositol isomer
ab120642	SQ 22536	Non-competitive adenylyl cyclase inhibitor

JAK/STAT

Cat No.	Compound	Description
ab120950	AG 490	JAK2/3 inhibitor
ab120666	Cryptotanshinone	STAT3 inhibitor with diverse biological activities
ab120951	Nifuroxazide	JAK/STAT signaling inhibitor. Nitrofuran antibiotic
ab120952	Stattic	Selective STAT3 inhibitor

MAPK

Cat No.	Compound	Description
ab120495	Anisomycin	Protein synthesis inhibitor
ab120365	CGP 57380	MNK inhibitor
ab120716	(-)-Epigallocatechin Gallate	Potent anti-oxidant flavonoid
ab120863	Hydralazine hydrochloride	DNA methylation inhibitor. Anti-hypertensive agent
ab120710	Isoprenaline hydrochloride	Non selective β-adrenoceptor agonist
ab120653	2-Methoxyestradiol	Potent antitumor and antiangiogenic agent
ab120721	Myricetin	Potent anti-neoplastic, anti-oxidant and anti-inflammatory agent
ab120234	PD 98059	MEK1 inhibitor
ab120638	SB 202190	Highly selective, potent, cell permeable p38 MAP kinase inhibitor
ab120162	SB 203580	p38 MAP kinase inhibitor
ab120235	SB 203580 hydrochloride	p38 MAP kinase inhibitor; water soluble
ab120836	SD 169	Potent, selective and ATP competitive p38α MAPK inhibitor
ab120082	SL 327	MEK inhibitor
ab120746	Sodium salicylate	Cell permeable anti-inflammatory agent
ab120065	SP600125	JNK inhibitor
ab120650	Sulindac sulfide	Active metabolite of Sulindac. COX-1/ 2 inhibitor.
ab120835	TCS JNK 5a	Selective JNK2/3 inhibitor
ab120241	U0126	Selective MKK inhibitor
ab120428	ZM 336372	Potent, selective c-Raf inhibitor

Nitric oxide & oxidative stress

Cat No.	Compound	Description
ab120165	1400W	Selective iNOS inhibitor
ab120123	Aminoguanidine hydrochloride	NOS inhibitor
ab120750	L-Arginine	Precursor to nitric oxide synthesis
ab120976	Bisdemethoxycurcumin	Apoptotic anti-cancer, anti-inflammatory andanti-oxidant curcuminoid
ab120973	Chlorogenic acid hemihydrate	Antioxidant with a variety of biological effects
ab120653	2-Methoxyestradiol	Potent antitumor and antiangiogenic agent
ab120661	Minocycline hydrochloride	Antibiotic. Demonstrates multiple effects.
ab120137	NG-Monomethyl-L-arginine, monoacetate salt (L-NMMA)	NOS inhibitor
ab120721	Myricetin	Potent anti-neoplastic, anti-oxidant and anti-inflammatory agent
ab120958	(±)-Naringenin	Citrus flavonoid. Antioxidant, anti-inflammatory
ab120864	Nicotinamide	Amide form of vitamin B₃
ab120233	7-Nitroindazole	NOS inhibitor
ab120136	Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME)	NOS inhibitor
ab120285	S-Nitrosoglutathione (SNOG)	NO donor
ab120726	Resveratrol	Antioxidant polyphenol with a multitude of biological activities
ab120014	SNAP	NO donor
ab120057	Spermidine hydrochloride	Endogenous polyamine. nNOS inhibitor
ab120747	Trolox	Antioxidant vitamin E derivative

PI3K/Akt

Cat No.	Compound	Description
ab120964	Crosstide	Akt peptide substrate
ab120965	Crosstide (biotinylated)	Akt peptide substrate, biotinylated
ab120960	Indirubin	Potent cyclin-dependent kinase and GSK-3β inhibitor
ab120243	LY 294002	PI3-kinase inhibitor
ab120375	Okadaic acid	PP1 and PP2A inhibitor
ab120802	SC-66	Allosteric Akt inhibitor
ab120148	Wortmannin	PI3-kinase inhibitor

Wnt signaling

Cat No.	Compound	Description
ab120976	Bisdemethoxycurcumin	Apoptotic anti-cancer, anti-inflammatory and anti-oxidant curcuminoid

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NF-κB & IκB，Hedgehog，Inositol & cAMP，Nitric oxide 等通路调节剂

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