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人间充质干细胞成软骨诱导试剂盒
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小分子化合物在干细胞定向分化诱导研究中的应用
1795 人阅读发布时间：2017-05-02 14:57
干细胞即为起源细胞，它是一类具有多向分化潜能和自我复制能力的原始未分化细胞，是形成哺乳类动物的各组织器官的原始细胞。
| 货号 | 产品名 | CAS | 简介 |
| abs810550 | CHIR99021 | 252917-06-9 | purity>98%；Highly selective GSK-3 inhibitor; enables reprogramming of mouse embryonic fibroblasts into iPS cells |
| abs810640 | Y-27632 2HCL | 129830-38-2 | purity>99.5%；Selective p160ROCK inhibitor; increases survival rate of human embryonic stem cells undergoing cryopreservation |
| abs810456 | Thiazovivin | 1226056-71-8 | purity>98%；Improves the efficiency of fibroblast reprogramming and induction of iPSCs |
| abs810490 | PD-0325901 | 391210-10-9 | purity>99%；Selective inhibitor of MEK1/2; enhances generation of iPSCs |
| abs810481 | SB-431542 | 301836-41-9 | purity>99%, Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7 |
| abs810300 | CASIN | 425399-05-9 | purity>98%；Cdc42 GTPase inhibitor; functionally rejuvenates aged HSCs |
| abs810529 | Dorsomorphin 2HCl | 1219168-18-9 | purity>98%；a potent inhibitor of AMP-activated protein kinase (AMPK) (Ki=109nM) and bone morphogenic protein (BMP) signaling |
| abs810528 | LDN-193189 | 1062368-24-4 | purity>98%；BMP pathway inhibitor Inhibits ALK2, ALK3, ALK6 |
| abs810568 | StemRegenin 1 (SR1) | 1227633-49-9 | purity>98%；Aryl hydrocarbon receptor (AhR) antagonist |
| abs810756 | A77-01 | 607737-87-1 | purity>98%；An inhibitor of ALK5 with an IC50 of 25nM |
| abs810546 | CHIR98014 | 252935-94-7 | purity>99%, A selective and ATP-competitive inhibitor of GSK-3β,higher activity than CHIR99021 |
| abs812010 | BIO | 667463-62-9 | purity>98%；Potent, selective GSK-3 inhibitor |
| abs812230 | GDC-0449 | 879085-55-9 | Purity>98%；GDC 0449 is a potent antagonist of SMO that acts in a biphasic manner |
| abs815959 | NVP-LDE225 | 956697-53-3 | purity>99%,；A novel and specific, orally bioavailable Smo inhibitor with an IC50 of 11 nM. |
| abs810496 | Repsox (ALK5 INHIBITOR) | 446859-33-2 | purity>98%；Selective TGF-βRI inhibitor; enhances reprogramming efficiency |
| abs810648 | XAV-939 | 284028-89-3 | purity>99%；Tankyrase inhibitor; promotes cardiomyogenesis |
| abs810473 | DAPT | 208255-80-5 | purity>98%；A gamma-secretase and indirectly Notch, LDL receptor-related protein, E-cadherin and ErbB-4 inhibitor. |
| abs810007 | GDC-0941 | 957054-30-7 | purity>98%；Anovel class I selective PI3K inhibitor |
| abs810001 | LY-294002 | 154447-36-6 | purity>99%；Selective PI 3-kinase inhibitor; suppresses proliferation of mESCs |
| abs810609 | KY02111 | 1118807-13-8 | Purity>98%；Promotes differentiation of human ESCs and iPSCs into cardiomyocytes when used after day three in culture |
| abs810444 | IWR-1-endo | 1127442-82-3 | Purity>99%；Axin stabilizer; promotes β-catenin phosphorylation |
| abs810509 | IWP-2 | 686770-61-6 | purity>98%；Inhibitor of Wnt processing and secretion; suppresses self-renewal in R1 ESCs |
| abs812022 | GANT-61 | 500579-04-4 | Purity>98%；GLI antagonist; inhibits Hh signaling |
| abs810002 | SB-203580 | 152121-47-6 | Purity>99%；Selective inhibitor of p38 MAPK; stimulates neural stem cell proliferation |
| abs810698 | BIX 01294 | 935693-62-2 | purity:>98%；G9a-like protein and G9a HMTase inhibitor; potentiates induction of iPSCs |
| abs810585 | JW 55 | 664993-53-7 | purity:>98%；Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2) |
| abs810564 | PluriSIn 1 (NSC 14613) | 91396-88-2 | purity:>98%；Inhibitor of SCD1; selectively eliminates undifferentiated hPSCs from culture |
| abs810337 | Purmorphamine | 483367-10-8 | purity:>98%；Smo receptor agonist; induces differentiation of mesenchymal progenitor cells into osteoblasts |
| abs810578 | AR-A014418 | 487021-52-3 | purity>98%；Selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). |
| abs810657 | A 769662 | 844499-71-4 | purity:>98%；Potent AMPK activator; inhibits MSC proliferation |
| abs810497 | GW788388 | 452342-67-5 | purity>98%；Potent inhibitor of transforming growth factor-β type I receptor (ALK5) (IC50 values are 18 and 93 nM for ALK5 binding and for TGF-β cellular assay respectively). |
| abs810050 | Forskolin | 66575-29-9 | purity>98%；Used to reprogram mouse embryonic fibroblasts to induced pluripotent stem cells |
| abs47009824 | P7C3 | 301353-96-8 | purity:>98%；Neuroprotective compound; enhances neurogenesis in vivo |
| abs810621 | MK-2206 2HCl | 1032350-13-2 | purity:>98%；An Akt inhibitor |
| abs47025692 | ID-8 | 147591-46-6 | purity:>98%；Sustains self-renewal and pluripotency of ESCs |
| abs810562 | FH1(BRD-K4477) | 2719-5-3 | purity:>98%；Enhances differentiation of induced pluripotent stem cells (iPSCs) to hepatocytes and promotes the maturation of iPSC-derived hepatocytes. |
| abs810581 | Reversine | 656820-32-5 | purity:>98%；The first organic molecule that has been demonstrated to reverse the cellular differentiation process. |
| abs810498 | RG-108 | 48208-26-0 | purity:>98%；Non-nucleoside DNA methyltransferase inhibitor; enhances efficiency of iPSC generation |
| abs810639 | Wnt-C59 | 1243243-89-1 | purity:>98%；Wnt signaling inhibitor; induces differentiation of iPSCs to cardiomyocytes |
| abs810254 | OAC-1 | 300586-90-7 | purity:>98%；Enhances and accelerates iPSC reprogramming. |
| abs810255 | OAC-2 | 6019-39-2 | purity:>98%；Enhances and accelerates iPSC reprogramming. |
| abs810420 | ICG-001 | 847591-62-2 | purity:>99%；Selectively inhibits β-catenin/CBP interaction; displays no effect on β-catenin/p300 interaction. Exhibits growth inhibitory effects in colon carcinoma cell lines (SW480 and HCT-116 cells); also displays efficacy in Min mouse and nude mouse SW620 xenograft models. |
| abs810674 | Kenpaullone | 142273-20-9 | purity:>98%；Potent cyclin-dependent kinase inhibitor. Also inhibits GSK-3 |
| abs810742 | Go-6983 | 133053-19-7 | purity:>98%；Optimizes naïve human pluripotent stem cell growth and viability; PKC inhibitor |
| abs810148 | Napabucasin (BBI608) | 83280-65-3 | purity:>98%；Napabucasin (BBI608) is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells. |
| abs814131 | ITE | 448906-42-1 | purity:>98%；ITE is an Endogenous aryl hydrocarbon receptor (AhR) agonist (Ki = 3 nM). |
| abs42013064/65 | Alsterpaullone | 237430-03-4 | purity:>98%；Alsterpaullone is a potent ATP-competitive and cell cycle cyclin-dependent kinase inhibitor, that is reported to be the most active Paullone. |
| abs47028325 | EW-7197 | 1352608-82-2 | purity:>98%；EW-7197 is a potent ALK5 inhibitor. |
| abs810389 | SB-505124 | 694433-59-5 | purity:>98%；SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6. |
| abs814385 | XMU-MP-1 | purity:>98%；XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM against MST1 and MST2, respectively. | |
| abs814351 | IWP-4 | 686772-17-8 | purity:>98%；Wnt Inhibitor IWP-4 is a potent inhibitor of Wnt/β-catenin signaling (IC50 = 25 nM). |
| abs816009 | CHIR-99021 HCl | 252917-06-9 (free base) | purity:>98%；CHIR-99021 HCl is a glycogen synthase kinase 3 beta inhibitor that has antiproliferative activity in vitro and in vivo. |
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生化试剂（60万种）、抗体（10万种）、细胞因子、二抗、ECL发光液、蛋白marker、激动剂、抑制剂、凋亡试剂盒、BSA、动植物提取物、蛋白酶K...
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