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mGlu、Ionotropic、Glutamate & GABA 等通路调节剂组合

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mGlu、Ionotropic、Glutamate & GABA 等通路调节剂组合

1161 人阅读发布时间：2014-09-24 11:12


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Glutamate and GABA Kits

A range of biochemical tool kits, designed to be:
♦ Economical - Good value and no wastage ♦ Convenient - No weighing, no fuss! ♦ Simple - Products are provided as an exact weight sothat addition of 1 ml or 0.5 ml of solvent provides a stock solution of 5 mM or 10 mM respectively

mGlu Agonists Kit (ab120321)
A collection of 7 agonists and modulators for a range of mGlu receptor subtypes. The kit contains:

Product name	Receptor	Description	Product code
(S)-3,5-DHPG	mGlu_1,5	Selective group I agonist	ab120007
(R,S)-CHPG sodium salt	mGlu₅	Water-soluble form of (R,S)-CHPG (ab120039), a selective agonist	ab120221
LY 379268	mGlu_2,3	Highly potent and systemically active agonist	ab120196
L-AP4	mGlu_4,6,7,8	Selective group III mGlu receptor agonist	ab120002
VU0155041 sodium salt	mGlu₄	Water-soluble, positive allosteric selective modulator	ab120248
AMN082 dihydrochloride	mGlu₇	Potent, selective, orally active and brain penetrant agonist	ab120011
(S)-3,4-DCPG	mGlu₈	Potent, selective mGlu_8a agonist	ab120006

mGlu Antagonists Kit (ab120322)
A collection of 6 antagonists for mGlu receptor subtypes. The kit contains:

Product name	Receptor	Description	Product code
LY 341495 sodium salt	All mGlu(mGlu_{1,2,3,4,5,6,7,8})	Potent, selective group II antagonist. Group III antagonist at higher concentrations.	ab120400
(R,S)-MCPG sodium salt	mGlu_1,2,3,5	Group I / group II mGlu receptor antagonist	ab120252
LY 367385 sodium salt	mGlu₁	Potent, selective mGlu₁a antagonist	ab120418
YM 298198 hydrochloride	mGlu₁	Potent, selective, water-soluble, non-competitive mGlu₁ antagonist	ab120015
MTEP hydrochloride	mGlu₅	Brain penetrant, potent, selective and non-competitive mGlu₅ receptor antagonist	ab120035
MMPIP	mGlu₇	Potent, selective allosteric antagonist	ab120245

Ionotropic Agonists Kit (ab120323)
A collection of 8 agonists, antagonists and potentiators at AMPA, Kainate and NMDA receptors. The kit contains:

Product name	Receptor	Description	Product code
(S)-AMPA	AMPA	AMPA agonist	ab120005
(S)-5-Fluorowillardiine hydrochloride	AMPA	Potent, selective AMPA agonist	ab120399
Cyclothiazide	AMPA	Positive allosteric modulator of AMPA receptors	ab120061
Aniracetam	AMPA	Nootropic, positive allosteric modulator of AMPA receptors	ab120316
Kainic acid	Kainate	Prototypic agonist at the kainate class of ionotropic glutamate receptors	ab120100
(S)-5-Iodowillardiine hydrochloride	Kainate	Selective GluK1 (formerly GluR5) kainate receptor agonist	ab120401
NMDA	NMDA	Excitotoxic amino acid	ab120052
D-serine	NMDA	Agonist at the NMDA glycine binding site and the inhibitory post-synaptic glycine receptor	ab120048

Glutamate & GABA Antagonists Kit (ab120376)
A collection of 5 antagonists for Glutamate and GABA receptors. The kit contains:

Product name	Receptor	Description	Product code
LY 341495 sodium salt	All mGlu(mGlu_{1,2,3,4,5,6,7,8})	Potent, selective group II antagonist. Group III antagonist at higher concentrations.	ab120400
D-AP5	NMDA	Competitive NMDA receptor glutamate site antagonist	ab120003
NBQX disodium salt	AMPA/Kainate	Water-soluble, potent, selective and competitive AMPA/kainate receptor antagonist	ab120046
(-)-Bicuculline methochloride	GABA_A	Water-soluble GABA_A antagonist	ab120110
CGP 52432	GABA_B	Potent, selective GABA_B antagonist	ab120330

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